The No. 16 Stanford Cardinal and the Notre Dame Fighting Irish will both be trying to pick up a win on Saturday when they battle at Notre Dame Stadium (3:30 pm ET, NBC).

The Cardinal are a 5-point favorite and the over/under total is 58.5.

Notre dame has dominated the past 10 head-to-head matchups, going 8-2 SU and &-3 ATS in that span. The teams met last season, when the Cardinal beat the Fighting Irish 45-38 on Nov. 28, but failed to cash as a 10-point home favorite. The score went over the total of 64.

Stanford won beat Wake Forest 68-24 on Saturday, covering as a 17.5-point favorite, while the 92 combined points took the game over the total.

Notre Dame was a 34-31 loser Saturday against rival Michigan State Spartans. But the Fighting Irish covered the 3.5–point spread as underdogs and the score went over.

Stanford (2-0 SU, 1-0 ATS) has won 2 straight games. Notre Dame (1-2 SU, 1-2 ATS) has lost 2 straight games.
The total has gone over in 4 of Stanford’s last 5 games on the road, and Stanford is 4-12 SU in its last 16 games on the road.

Notre Dame is 1-5 ATS in its last 6 games at home, and the total has gone under in 5 of Notre Dame’s last 6 games at home.